Dr. Vijay K. Singh

Infectious Diseases & Antimicrobial Resistance. Details will be updated soon....

Faculty Appointments:

  • Assistant Professor II- Institute of Advanced Study in Science and Technology, Guwahati, India (10/2023-now)
  • Faculty, Instructor in surgery-  Massachusetts General Hospital & Harvard Medical School, Boston, USA (9/2023-10/2023)
  • Scientist- Shriners Hospital for Children, Boston, USA (5/2023-10/2023)

Postdoctoral Training:

  1. Research Fellow- Department of Surgery, Massachusetts General Hospital & Harvard Medical School, Boston, USA (01/2018-08/2023)
  2. Research Fellow- Department of Microbiology, Harvard Medical School, Boston, USA (01/2018-08/2023)
  3. Research Fellow- Shriners Hospital for Children, Boston, USA (05/2018-05/2023)
  4. National Postdoctoral Fellow-CSIR-Institute of Microbial Technology, Chandigarh, India (04/2017-01/2018)

Education:

  1. Ph.D.  in Biotechnology- CSIR-Central Salt & Marine Chemicals Research Institute/ MKBU, Bhavnagar, India (2017)
  2. M. Sc in Biotechnology- Lalit Narayan Mithila University, Darbhanga, India (2010)
  3. B. Sc in Botany (Hons)- C. M. Science Collage, Darbhanga, India (2007)

Awards and Honors:

  1. Honors Bachelor of Science- LN Mithila University, Darbhanga, India (2007)
  2. Best publication award of the institute- (Highest Impact Factor publication in Biological Sciences) CSIR-Central Salt & Marine Chemicals Research Institute, India (2016)
  3. SERB-NPDF- Science and Engineering Research Board, Department of Science and Technology, Government of India (2016)
  4. Indo-U.S. Postdoctoral Fellow-Indo-U.S. Science and Technology Forum and Science and Engineering Research Board, Department of Science and Technology, Government of India (2017)

Administrative Leadership Positions:

  1. Research Safety Committee Member- Massachusetts General Hospital and Massachusetts General Research Institute, Boston (2021-2023)
  2. Covid Safety Officer- Massachusetts General Hospital and Massachusetts General Research Institute, Boston (2021-2023)
  3. Biosafety Officer- Molecular Surgical Laboratory, Massachusetts General Hospital, Boston (2021-2023)
  4. Radiation Safety Officer- Molecular Surgical Laboratory, Massachusetts General Hospital, Boston (2021-2023)
  5. In charge-Controlled Substances-Molecular Surgical Laboratory, Massachusetts General Hospital, Boston (2021-2023)

Editorial Roles:

  1. Editor- BMC Microbiology
  2. Associate editor-  Frontiers in Medical Technology (Animal Models in Medical Translation)
  3. Guest editor- Frontiers in Cellular and Infectious Microbiology (Bacteria and Host)
  4. Topic Editor-Special Research Topic “Bacterial Quorum Sensing: Disease, Treatment and Beyond”, Frontiers in Cellular and Infection Microbiology
  5. Review Editor- Frontiers in Microbiology (Antimicrobials, Resistance, and Chemotherapy)
  6. Review Editor- Frontiers in Cellular and Infection Microbiology (Biofilm)

Ad hoc Reviewer:

  1. Frontiers in Chemistry
  2. Frontiers in Plant Science
  3. PlosOne
  4. Microbiology Spectrum
  5. Scientific Report
  6. Journal of Food Science and Technology
  7. Journal of Applied Microbiology

1. Arunava Bandyopadhaya, Vijay Kumar Singh, Arijit Chakraborty, A. Aria Tzika, and Laurence G Rahme (2022). Immunometabolic hijacking of immune cells by a Pseudomonas aeruginosa quorum-sensing signal. bioRxiv, DOI:10.1101/2021.10.03.462785.

2. Vijay K. Singh, Marianna Almpani, Kelsey M. Wheeler, and Laurence G. Rahme (2023). Interconnections of Pseudomonas aeruginosa quorum sensing systems in intestinal permeability and inflammation. mBio, 14, e03524-22. (IF- 7.86)

3. Vijay K. Singh, Marianna Almpani, Damien Maura, Tomoe Kitao, Livia Ferrari, Stefano Fontana, Gabriella Bergamini, Elisa Calcaterra, Chiara Pignaffo, Michele Negri. et. al., (2022). Tackling Recalcitrant Pseudomonas aeruginosa Infections In Critical Illness via Anti-virulence Monotherapy. Nature Communications, 13, 5103. (IF- 17.69)

4. Ankita Alexander, Vijay Kumar Singh, and Avinash Mishra (2022). Introgression of a novel gene AhBINR differentially expressed during Brachybacterium saurashtrense-Arachis hypogaea interaction gene AhBINR enhances plant performance under nitrogen starvation and salt stress in tobacco. Plant Science, 324, 111429. (IF- 5.36)

5. Vijay Kumar Singh, Marianna Almpani and Laurence G. Rahme. (2021) The role of common solvents against Pseudomonas aeruginosa-induced pathogenicity in a murine burn-site infection model. Microbiology Spectrum, 2, e00233-21. (IF-9.04)

6. Tchakal-Mesbahi, Asma, Merzak Metref, Vijay Kumar Singh, Marianna Almpani, and Laurence G. Rahme. (2021). Characterization of antibiotic resistance profiles in Pseudomonas aeruginosa isolates from burn patients. Burns, 8,1833-1843. (IF-2.60)

7. Ankita Alexander, Vijay Kumar Singh, and Avinash Mishra (2021). Overexpression of differentially expressed AhCytb6 gene during plant-microbe interaction improves tolerance to N2 deficit and salt stress in transgenic tobacco. Scientific Reports, 11, 1- 20. (IF-4.99)

8. Ankita Alexander, Vijay Kumar Singh, and Avinash Mishra (2021). Interaction of the novel bacterium Brachybacterium saurashtrense JG06 with Arachis hypogaea leads to changes in physio-biochemical activity of plants to cope with nitrogen starvation conditions. Plant Physiology and Biochemistry, 166, 974-984. (IF-5.43)

9. Almpani, Marianna, Asma Tchakal-Mesbahi, Merzak Metref, Vijay K. Singh, and Laurence G. Rahme. (2020) First Report of Pseudomonas aeruginosa Isolates Harboring the CTX-M2 and PER genes in Algeria. Open Forum Infectious Diseases, 7, S461. (IF-4.42)

10. Ankita Alexander, Vijay Kumar Singh, and Avinash Mishra (2020). Halotolerant PGPR Stenotrophomonas maltophilia BJ01 induces salt tolerance by modulating physiology and biochemical activities of Arachis hypogaea. Frontiers in Microbiology 11, 2530. (IF-6.06)

11. Ankita Alexander, Vijay Kumar Singh, Avinash Mishra, and Bhavanath Jha (2019). Plant growth promoting rhizobacterium Stenotrophomonas maltophilia BJ01 augments endurance against N2 starvation by modulating physiology and biochemical activities of Arachis hypogea. PloS one, 14, e0222405. (IF-3.75)

12. Vijay Kumar Singh, Avinash Mishra, and Bhavanath Jha (2019). 3-Benzyl-hexahydro- pyrrolo[1,2-a] pyrazine-1,4-dione extracted from Exiguobacterium indicum showed anti- biofilm activity against Pseudomonas aeruginosa by attenuating the quorum sensing. Frontiers in Microbiology. 10, 1269. (IF-6.06)

13. Vijay Kumar Singh, Avinash Mishra, and Bhavanath Jha (2017). Anti-quorum sensing and anti- biofilm activity of Delftia tsuruhatensis extract by attenuating the quorum sensing-controlled virulence factor production in pseudomonas aeruginosa. Frontiers in Cellular and Infection Microbiology 7, 337. (IF-6.07)

14. Vijay Kumar Singh, Avinash Mishra, Intesaful Haque and Bhavanath Jha (2016). A novel transcription factor-like gene SbSDR1 acts as a molecular switch and confers salt and osmotic endurance to transgenic tobacco. Scientific Reports 6, 31686. (IF-4.99)

15. Bhavanath Jha, Vijay Kumar Singh, Angelo Weiss, Anton Hartmann and Michael Schmid (2015). Zhihengliuella somnathii sp. nov., a halotolerant actinobacterium from the rhizosphere of a halophyte Salicornia brachiata. International Journal of Systematic and Evolutionary Microbiology 65, 3137-3142. (IF-2.68)

16. Narendra Singh Yadav, Vijay Kumar Singh, Dinkar Singh, and Bhavanath Jha. (2014). A Novel Gene SbSI-2 Encoding Nuclear Protein from a Halophyte Confers Abiotic Stress Tolerance in
E. coli and Tobacco. PloS One 9, e101926. (IF-3.75)

17. Kumari Kavita, Vijay Kumar Singh, Avinash Mishra, and Bhavanath Jha (2014). Characterisation and anti-biofilm activity of extracellular polymeric substances from Oceanobacillus iheyensis. Carbohydrate polymers, 101, 29-35. (IF-10.72)

18. Kumari Kavita, Vijay Kumar Singh, and Bhavanath Jha. (2014). 24-Branched Δ5 sterols from Laurencia papillosa red seaweed with antibacterial activity against human pathogenic bacteria. Microbiological research 169, 301-306. (IF-5.07)

19. Vijay Kumar Singh, Kumari Kavita, Rathish Prabhakaran, and Bhavanath Jha. (2013). Cis-9- octadecenoic acid from the rhizospheric bacterium Stenotrophomonas maltophilia BJ01 shows quorum quenching and anti-biofilm activities. Biofouling, 29, 855-867. (IF-3.79)

Coming soon....

Will be updated....

Singh Lab will start hiring at multiple levels soon. Please reach out at vijay.singh@iasst.gov.in if you are interested in Infectious Diseases, Quorum Sensing, Biofilm, Host-Microbe interaction, and Antimicrobial Resistance.