Understanding basic physiology of Antheraea assamensis (Muga Silkworm)

Seri-Biotechnology laboratory research is to understand basic physiology of Antheraea assamensis (Muga Silkworm), which is in serious threat of extinction and its interaction with pathogens in a broad sense. We are interested in understanding how Muga silkworm respond to pathogens, but also how other factors (other pathogens, different host plant, etc.) can influence in the interaction. Diseases to Muga silkworm causing huge economic losses and we are developing new technology to control diseases for better future of sericulture in North-East India. First, we have isolated and characterized a new Cytoplasmic Polyhedrosis Virus (Cypovirus) from Muga silkworm. We have characterized its molecular structure and biological function to understand virus and its pathogenesis to Muga silkworm (one manuscript in preparation for submission; grant proposal submitted to CRG-SERB-DST, as PI, 76 lakhs). Second, we have developed a non-toxic, environment friendly Titanium Dioxide (TiO2) nanoparticle-based formulation to boost immune system of Muga silkworm against cypovirus. The new technology in proof of concept (POC) stage and will be commercialize after validation (one manuscript and provisional patent in preparation for submission; grant submitted to DBT-BIRAC as PI-in review, 25 lakhs).