Former Director’s (since taking over of IASST by DST, Govt. of India)
| Sl. No. | NAME | PERIOD |
| 01 | Prof. Joyanti Chutia | 09/03/2009 to 31/07/2012 |
| 02 | Prof. Binod Ch. Tripathy (i/c) | 01/08/2012 to 23/06/2013 |
| 03 | Dr. Narayan Chandra Talukdar | 24/06/2013 to 29/02/2020 |
| 04 | Prof. Heremba Bailung (Additional Charge) | 01/03/2020 to 22/11/2020 |
| 05 | Prof. Ashis Kumar Mukherjee | 23/11/2020 to 22/11/2025 |
Former Director’s (before taking over of IASST by DST, Govt. of India)
| Sl. No. | NAME | PERIOD |
| 01 | Dr. Jamini Mohan Choudhury | 03/11/1979 to 30/04/1985 |
| 02 | Prof. Jyoti Prasad Medhi | 01/05/1985 to 30/04/1987 |
| 03 | Prof. Binoy Kr. Tamuli | 01/05/1987 to 10/07/1987 |
| 04 | Dr. Pratul Goswami | 31/07/1987 to 29/01/1996 |
| 05 | Prof. Kamal Ch. Barua | 30/01/1996 to 15/05/2000 |
| 06 | Prof. Kishori Mohan Pathak (i/c) | 16/05/2000 to 31/07/2001 |
| 07 | Dr. Mahanta Kr. Kalita (i/c) | 01/08/2001 t0 31/12/2001 |
| 08 | Prof. Narendra Nath Dass | 01/01/2002 to 30/09/2005 |
| 09 | Prof. Joyanti Chutia | 30/09/2005 to 08/03/2009 |