Herbal medicine loaded smart bandage for wounds

This work demonstrates the development of a pH responsive smart drug delivery system. In this work a hybrid cotton patch nanocomposite incorporated with jute carbon dots was fabricated to carry out the drug release study. Notably, jute was used for the first time as a precursor in synthesizing fluorescent carbon dots and water was used as the dispersion medium. A herbal formulation neem leaf (Azadirachta indica) extract was taken as the model drug to exemplify the release study. It was found in in-vitro study that the hybrid jute carbon dot-cotton patch showed two distinct release profiles at pH 5 and 7, where the release shown to be higher at pH 5 than at pH 7. The development of such a stimuli-responsive behavior of hybrid cotton patch would pave the way for utilizing systems as smart wound-dressing material using sustainable materials like jute and cotton. The work was published in ACS Sustainable Chem. Eng. 2020, https://dx.doi.org/10.1021/acssuschemeng.0c01221

The scheme depicting the fabrication of pH responsive cotton patch