Ashis K. Mukherjee

THRUST AREAS OF RESEARCH

A.Traditional and Modern Drug Discovery and Disease Diagnosis: 

  1. Purification and characterization of snake venom and scorpion venom toxins
  2. Development of multidimensional analytical methods for quality control and quality assessment of commercial anti-snake and anti-scorpion antivenoms.
  3. New methods of antivenoms production and detection of snake venom.
  4. Exploration of snake venom proteins, bacterial proteases, and medicinal plant components for the prevention and/or treatment of thrombosis-associated cardiovascular disorders, cancer, and neurodegenerative disorders.
  5. Diagnostic application of snake venom toxins for the ex vivo and in vivo detection of breast cancer.
  6. Peptidomimetic.

B. Biodiversity and Eco-System Research:

  1. Proteomic analysis to unveil the geographical and species-specific differences in snake venom composition and its impact on clinical manifestations of snakebite and antivenoms treatment.
  2. Exploration of hydrocarbons degrading bacteria for the bioremediation of petroleum-oil contaminated hydrocarbons in soil and water.
  3. Proteomic analysis to identify the polyaromatic hydrocarbons (PAHs) degradation pathway(s) in bacteria.
  4. Purification, characterization, and industrial application of microbial biosurfactant and enzymes.
  5. Phytochemical characterization of edible and toxic mushrooms grown in Assam.

C. Interdisciplinary Center for Research:

  1. Nano biotechnology.
  2. Application of biophysical techniques for the quality assessment of commercial antivenoms.

Current Position:   Director, Institute of Advanced Study in Science and Technology (From 23 November 2020 to till date)

Other Affiliations:

  • Professor, Department of Molecular Biology and Biotechnology, Tezpur University, Assam, India (On deputation)
  • Outstanding Professor, Faculty of Biological Sciences, Academy of Scientific & Innovative Research (AcSIR), Govt. of India.
  • Associate Faculty (Professor), School of Biological Sciences, University of Northern Colorado, Greeley, USA.

Past Administrative Experience:   

  • Dean, Research and Development, Tezpur University (2016-2019)
  • Head and Coordinator, DBT Nodal Cell for Medical Colleges and Biomedical Research Institutes   of NE India (A Unit of DBT, Govt. of India), Tezpur University (2009- 2018)
  • Head, ONGC Center for Petroleum Biotechnology, Tezpur University (2014-2017)
  • Head and Coordinator, Department of Molecular Biology and Biotechnology, Tezpur University (2008-2011)

Academic Qualification:

  1. B. Sc. (Chemistry Hons) in 1990 from Banaras Hindu University, Varanasi securing first class first position
  2. M. Sc. (Biochemistry) in 1992 from Banaras Hindu University, Varanasi securing first class first position
  3. Ph.D. in 1998 from Department of Biochemistry, Burdwan Medical College, Burdwan University, India.
  4. D. Sc. (Biotechnology) from Calcutta University, Kolkata in 2017

Employment Details (Starting with Present Employment):

  1. Director, Institute of Advanced Study in Science and Technology, Guwahati, India (23 November 2020 to till date)
  2. Professor, Department of Molecular Biology and Biotechnology, Tezpur University, Assam (2009 -2020)
  3. Visiting Scientist, School of Biological Sciences, University of Northern Colorado, Greeley, USA (2011-2020)
  4. Associate Professor, Department of MBBT, Tezpur University, Assam (2007 -2009)
  5. Reader, Dept. of MBBT, Tezpur University, Assam (2004- 2006)
  6. Sabbatical Visitor, Department of Molecular, Microbial and Structural Biology,  School of Medicine, the University of Connecticut Health Center, Farmington, CT, USA (2002- 2003)
  7. Senior Lecturer, Department of MBBT, Tezpur University, Assam (2001-  2004)
  8. Lecturer, Department of MBBT, Tezpur University, Assam (1997- 2001)

Honors & Awards Received:

Prof. Ashis K. Mukherjee receiving the Visitor’s Award, 2018 for research in the field of Basic and Applied Sciences from the Honorable President of India at the Rashtrapati Bhawan

Prof. Ashis K. Mukherjee received the Visitor's Award, 2018 for Research in the field of Basic and Applied Sciences from the Honorable President of India at the Rashtrapati Bhawan.             

  

Tata Innovation Fellowship by DBT in 2018                                     INSA Teachers Award in 2018

Professional Recognition/Honors/Awards/ Academic Achievements

1990

Banaras Hindu University (B.H.U.) cash prize recipient for securing first class first position in B. Sc.  (Chemistry Hons.) Examination

1991

Qualified the UGC-CSIR NET for Junior Research Fellowship (JRF) and   eligibility for lectureship in Life Sciences in Colleges and Universities of India

1992

B. H.U. Gold Medal for securing first class first position in M. Sc examination

1995

Certificate of Honor awarded by the Association of Medical Biochemists of India

1995

Young Scientist Gold Medal awarded by the Zoological Society of India

1997

Young Scientist Gold Medal awarded by the Physiological Society of India

1999

Young Scientist Award recipient in the Medical and Veterinary Sciences section of the Indian Science Congress Association

2001

BOYSCAST Fellowship (2002-2003) from the Department of Science and Technology (DST), Ministry of Science and Technology, Govt. of India for advanced research and training at the USA

2007

International Travel Award from the Department of Biotechnology, Govt. of India for presenting papers in an International conference at Seville, Spain

2008

Sectional Chairman, International CME & Conference on Snakes, Venom and Snakebite, Angamaly, Kerala

2008

Best Research Worker Award of Tezpur University

2009

Sectional Chairman, 54th Technical Meeting of Assam Science Society, Tezpur University

2009

Sectional Chairman, International Symposium on Environmental Pollution, Ecology and Human Health, S.V. University, Tirupati

2009

Co-Chairman, National Symposium on “Recent advances in snake venom research and snakebite therapy: National and International Perspectives”, Tezpur University

2010

Executive Committee Member, DBT Nodal Cell for Medical Colleges and Biomedical Research Institute of NE India, Department of Biotechnology, Ministry of Science and Technology, Govt. of India

2010

Dr. J. N. Baruah Memorial Science Award, 2010 in Biological Sciences by Assam Science Society, India

2010

Co-Chairman, National Conference on “Animal, Microbial, and Plant Toxins & Snakebite Management” held at IICB, Kolkata, and KPC Medical College and Hospital, Kolkata

2010

Sectional Committee Member (2011-2012), New Biology Section, Indian Science Congress Association, Kolkata

2011

DBT-CREST (Cutting Edge Research Enhancement and Scientific Training) Award 2010-11 from the Department of Biotechnology, Ministry of Science and Technology, Govt. of India for advanced training in the field of proteomics and drug discovery at UNC, USA

2011

Member, Star College Scheme, Department of Biotechnology, Ministry of Science and Technology, Govt. of India (2011-2014)

2012

Sectional Co-Chairman and Member of the Scientific Organization committee 17th World Congress on Venoms and Toxins organized by International Society on Toxinology, Honolulu, Hawaii, USA

2013

Unit of Excellence Award (2013) in NER of India by the Department of Biotechnology, Ministry of Science and Technology, Govt. of India

2014

Session Co-Chairman, Society of Biological Chemists (India) meeting of NE chapter, February 22, 2014, at North-East Institute of Science and Technology (CSIR), Jorhat

2014

National Bioscience Award for Career Development-2013 by Department of Biotechnology, Ministry of Science and Technology, Govt. of India

2014

Sreenivasaya Memorial Award-2014 for outstanding contribution in Biochemistry and allied sciences by the Society of Biological Chemists (India), held at KIIT University, Bhubaneswar, December 2014

2015

Cama Memorial Travel Grant for presenting a paper at the 18th World Congress of International Society on Toxinology, Oxford, UK from the Society of Biological Chemists (India), Bangalore

2015

International Travel Grant” for presenting a paper at the 18th World Congress of International Society on Toxinology, Oxford, UK awarded by the Department of Science and Technology (DST), Ministry of Science and Technology, Govt. of India.

2015

Sectional Co-Chairman, TSICO2015, 5th National Conference of Toxicological Society of India, organized by Little Flower Hospital, Cochin.

2015

Sectional Chairman, Recent Developments in Medical Biotechnology and Structure-Based Drug Designing [RDMBSBDD-2015] organized by IIT, Guwahati.

2016

Sectional Committee Member, Medical (including  Physiology) Section, Indian Science Congress Association, Kolkata (2016-2017)

2016

Chairman, National seminar on “Snake Venom Research and Snakebite Therapy: National and International Perspectives (SnakSymp2016)”, 22 to 24 November 2016, Tezpur University.

2017

Sectional Co-Chairman, New Biology Section, 104th Indian Science Congress, S. V. University, Tirupati, 3-7 January 2017

2017

Sectional Committee Member, New Biology Section, Indian Science Congress Association, Kolkata (2017-2018)

2017

Awarded  “Doctor of Science (D. Sc.)” in Biotechnology by Calcutta University

2018

Certificate of Appreciation by Tezpur University in recognition and appreciation of academic achievements.

2018

Received “Visitor’s Award for Research in Basic and Applied Sciences-2018” from the honorable President of India at Rashtrapati Bhawan on 2 May 2018

2018

Tata Innovation Fellowship (2017-18) by Department of Biotechnology, Ministry of Science and Technology, Govt. of India

2018

Elected Fellow Royal Society of Biology (FRSB)”, United Kingdom.

2018

INSA Teachers Award-2018 from Indian National Science Academy (INSA), New Delhi

2018

Indian Council of Medical Research Prize for Biomedical Research Conducted in Underdeveloped Areas (Prize for the year 2017) from ICMR, New Delhi

2018

Professor Sohail Ahmad Award-2018 from the Indian Academy of Biomedical Sciences, Lucknow for outstanding research contribution in the field of Biomedical Sciences (basic research).

2018

Expert Member, Department of Biotechnology, Ministry of Science and Technology, Govt. of India -NER Technical Expert Committee in the area of Knowledge Generation and Discovery Research, New Tools, and Techniques

2019

Nominated and sponsored by the Ministry of Human Resource Development (MHRD), Govt. of India for participation in three weeks program (two weeks in India and one week in abroad) on the “Leadership-for-Academicians Programme (LEAP)” organized by UGC-Human Resource Development Centre, JNU, New Delhi ( two weeks) and National University of Singapore, Singapore (one week). The main objective of LEAP is to prepare second-tier academic heads who are potentially likely to assume leadership roles (VC / Director) in the future

2019

National Task Force Expert Member “ICMR-National Task Force for Research on Snake Bite in India”, Indian Council of Medical Research, Ministry of Health and Family Welfare, Govt. of India.

2019

Elected Fellow, West Bengal Academy of Science and Technology, Kolkata, West Bengal, India.

2019

Expert Member, National Advisory Committee on Snakebite Envenoming, Department of Biotechnology, Ministry of Science and Technology, Govt. of India.

2020

Fellowship to cover travel, registration fee, and local hospitality from the North American Society of Toxinology (NAST), USA to deliver a lecture as a Plenary Speaker at Venom Week 2020 from 4-7 March, 2019 at Gainesville, Florida, USA.

2020

Core Member, Expert committee of DST-FIST (Fund for improvement of S&T Infrastructure in Universities and other higher educational institutions) program of Department of Science and Technology, Ministry of Science and Technology, Govt of India.

2021

Expert Member, World Health Organization, committee under Neglected Tropical Diseases for control and prevention of snakebite envenoming.

2021

Outstanding Professor in the Faculty of Biological Sciences,  The Academy of Scientific and innovative Research (AcSlR) (an Institution of National Importance established by an Act of Parliament, India).

Research Publications

2022-23

  1. Kakati, H., Giri, S., Patra, A., Taye, S. J., Agarwalla, D., Baruah, Choudhary, G., Kalita, B., Mukherjee, A. K. (2023). A retrospective analysis of epidemiology, clinical features of envenomation, and in-patient management of snakebites in a model secondary hospital of Assam, North-east India. Toxicon 230, 107175.IF: 3.035. Link: https://doi.org/10.1016/j.toxicon.2023.107175
  2. Patowary, R., Devi, A., Mukherjee, A. K. (2023). Advanced bio-remediation by an amalgamation of nanotechnology and modern artificial intelligence for efficient restoration of crude petroleum-oil contaminated sites: A prospective study. Journal of Environmental Science and Pollution Research (in press), IF: 5.190. Link: https://doi.org/10.1007/s11356-023-27698-4
  3. Devi, M. B., Sarma, H. K., Mukherjee, A. K., Khan, M.R. (2023). Mechanistic insights into immune-microbiota interactions and  preventive role of probiotics against autoimmune diabetes mellitus. Probiotics and Antimicrobial Proteins (in press), IF: 5.265. Link: https://doi.org/10.1007/s12602-023-10087-1
  4. Castro-Amorim, J, Oliveira, A., Mukherjee, A. K., Ramos, M. J, Fernandes, P. A. (2023). Unraveling the reaction mechanism of Russell’s viper venom factor X activator: a new paradigm for the reactivity of zinc metalloproteinases? Journal of Chemical Information and Modeling (in press). IF: 6.162. Link: https://doi.org/10.1021/acs.jcim.2c01156
  5. Castro-Amorim, J, Oliveira, A., Saulo, S., Andreimar; S., Mukherjee, A. , Ramos, M., Fernandes, P. A. (2023). Catalytically active snake venom PLA2 enzymes:  An overview of its elusive mechanisms of reaction. Journal of Medicinal Chemistry 66(8), 5364–5376. IF: 8.039. Link: https://doi.org/10.1021/acs.jmedchem.3c00097
  6. Puzari, U., Goswami, M., Rani Singh, K. R., Patra, A., Mukherjee, A. K. (2023). Computational and in vitro analyses to identify the anticoagulant regions of Echicetin, a snake venom anticoagulant C-type lectin (Snaclec): Possibility to develop anticoagulant peptide therapeutics? Journal of Bimolecular Structure and Dynamics (In press). IF: 5.235. Link: https://doi.org/10.1080/07391102.2023.2191138
  7. Madhubala, D., Patra, A., Islam,I., Saikia, K., Khan, M. R., Ahmed, S. , Borah, J. C.,  Mukherjee, A. K. (2023). Snake venom nerve growth factor-inspired designing of novel peptide therapeutics for the prevention of paraquat-induced apoptosis, neurodegeneration, and alteration of metabolic pathway genes in the rat pheochromocytoma PC-12 cell. Free Radical Biology and Medicine 197, 23-45. IF:8.101. Link: https://doi.org/10.1016/j.freeradbiomed.2023.01.019 
  8. Nath, S., Mukherjee, A. K. (2022). Ethno-medicines for the treatment of scorpion sting: A prospective study. Journal of Ethnopharmacology 305, IF: 5.195. Link: https://doi.org/10.1016/j.jep.2022.116078  
  9. Kalita, B. Utkin, Y. N., Mukherjee, A.K. (2022) Current Insights in the Mechanisms of Cobra Venom Cytotoxins and Their Complexes in Inducing Toxicity: Implications in Antivenom Therapy. Toxins 14, 839. IF: 5.075. Link: https://doi.org/10.3390/ toxins 14120839
  10. Patra, A., & Mukherjee, A. K. (2022). Mushroom mycetism–A neglected and challenging medical emergency in the Indian subcontinent: A road map for its prevention and treatment. Toxicon, 217, 56-77 Citation Index: NA, IF: 3.035. Link:https://doi.org/10.1016/j.toxicon.2022.07.014.
  11. Das, B., Patra, A., Puzari, U., Deb, P., & Mukherjee, A. K. (2022). In vitro laboratory analyses of commercial anti-scorpion (Mesobuthus tamulus) antivenoms reveal their quality and safety but the prevalence of a low proportion of venom-specific antibodies. Toxicon 215, 37-48. Citation Index: NA, IF: 3.035. Link: https://doi.org/10.1016/j.toxicon.2022.06.001.
  12. Kakati, H., Patra, A., Kalita, B., Chandra, A., Rapole, S., Mukherjee, A. K. (2022) A Comparison of two different analytical workflows to determine the venom proteome composition of Naja kaouthia from North-East India and immunological profiling of venom against commercial antivenoms. International Journal of Biological Macromolecules 208, 275-287. Citation Index: NA, IF: 6.953. Link: https://doi.org/10.1016/j.ijbiomac.2022.03.095  
  13. Das, S., Bhattacharjee, M. J., Mukherjee, A.K., Khan, M.R. (2022) Recent advances in understanding of multifaceted changes in the vaginal microenvironment: implications in vaginal health and therapeutics. Critical Reviews in Microbiology. Citation Index: NA, IF: 7.63. Link: https://doi.org/10.1080/1040841X.2022.2049696
  14. Puzari, U., Pedro, P. A., Mukherjee, A. K. (2022) Pharmacological re-assessment of traditional medicinal plants-derived inhibitors as antidotes against snakebite envenoming: A critical review. Journal of Ethnopharmacology 292, 115208. Citation Index: NA, IF: 4.27. Link: https://doi.org/10.1016/j.jep.2022.115208
  15. Baruah, J., Bardhan, P., Mukherjee, A. K., Deka, R.C., Mandal,M., Kalita, E. (2022) Integrated pretreatment of banana agrowastes: Structural characterization and enhancement of enzymatic hydrolysis of cellulose obtained from banana peduncle. International Journal of Biological Macromolecules 201, 298-307. Citation Index: NA, IF: 6.953. Link: https://doi.org/10.1016/j.ijbiomac.2021.12.179
  16. Mukherjee, A. K., Chanda, A., Mukherjee, I., Kumar, P. (2022) Characterization of lipopeptide biosurfactant produced by a carbazole degrading bacterium Roseomonas cervicalis: The role of biosurfactant in carbazole solubilization. Journal of Applied Microbiology 132(2), 1062-1078. Citation Index: NA, IF: 3.772. Link:10.1111/jam.15258
  17. Kumar, A., Joishy, T., Das, S., Kalita, M.C.,Mukherjee, A. K., Khan, M.R. (2022) A potential probiotic Lactobacillus plantarum JBC5 improves longevity and healthy aging by modulating antioxidative, innate Immunity and serotonin-signaling pathways in  Caenorhabditis elegans. Antioxidants  11(2), 268. Citation Index: NA, IF: 6.313. Link: https://doi.org/10.3390/antiox11020268
  18. Mukherjee, A. K., Chattopadhyay, D. J. (2022) Potential clinical applications of phytopharmaceuticals for the in-patient management of coagulopathies in COVID-19. Phytotherapy Research (Online ahead of print). Citation Index: NA, IF: 5.88. Link: 10.1002/ptr.7408

2020-21

  1. Kalita, B., Saviola, A.J., Samuel, S.P., Mukherjee, A. K. (2021) State-of-the-art review - A review on snake venom-derived antithrombotics: Potential therapeutics for COVID-19-associated thrombosis? International Journal of Biological Macromolecules 192,1040-1057. Citation Index: NA, IF: 6.953. Link: 10.1016/j.ijbiomac.2021.10.015
  2. Puzari, U., Fernandes, P. A., Mukherjee, A. K. (2021) Advances in the therapeutic application of small molecule inhibitors and repurposed drugs against snakebite. Journal of Medicinal Chemistry 64,13938-13979. Citation Index: NA, IF: 7.44Link: https://doi.org/10.1021/acs.jmedchem.1c00266
  3. Das, B., Saviola, A.J., Mukherjee, A.K. (2021) Biochemical and proteomic characterization, and pharmacological insights of Indian red scorpion venom toxins. Frontiers in Pharmacology 12, 2287. Citation Index: NA, IF: 5.81. Linkhttps://doi.org/10.3389/fphar.2021.710680 
  4. Mukherjee, A. K., MAckessy, S. P. (2021) Prevention and improvement of clinical management of snakebite in Southern Asian countries: A proposed road map. Toxicon 200,140-152. Citation Index: NA, IF: 3.003. Link: https://doi.org/10.1016/j.toxicon.2021.07.008   
  5. Patra, A., Kalita, B., Khadilkar, M. V., Salvi, N. C., Shelke, P.V., Mukherjee, A. K. (2021) Assessment of quality and pre-clinical efficacy of a newly developed polyvalent antivenom against the medically important snakes of Sri Lanka. Scientific Reports 11,18238. Citation Index: NA, IF: 4.37. Link: https://doi.org/10.1038/s41598-021-97501-2
  6. Islam, T., Madubala, D., Mukhopadhyay, R., Mukherjee, A. K. (2021) Transcriptomic and functional proteomics analyses to unveil the common and unique pathway(s) of neuritogenesis induced by Russell’s viper venom nerve growth factor in rat pheochromocytoma neuronal cells. Expert Review of Proteomics 18(6), 463-481. Citation Index: NA, IF:3.614. Linkhttps://doi.org/10.1080/14789450.2021.1941892 
  7. Patra, A., Herrera, M., Gutiérrez, J. M., Mukherjee, A. K. (2021) The application of laboratory-based analytical tools and techniques for the quality assessment and improvement of commercial antivenoms used in the treatment of snakebite envenomation. Drug Testing and Analysis 8,1471-1489. Citation Index: 02, IF: 3.345. Linkhttps://doi.org/10.1002/dta.3108 
  8. Patra, A., Mukherjee, A. K. (2021) Assessment of snakebite burdens, clinical features of envenomation, and strategies to improve snakebite management in Vietnam. Acta Tropica 216, 105833. Citation Index: 02, IF: 3.112. Linkhttps://doi.org/10.1016/j.actatropica.2021.105833
  9. Kalita, B., Saviola, A. J., Mukherjee, A. K. (2021) From venom to drugs: A review and critical analysis of Indian snake venom toxins envisaged as anti-cancer drug prototypes. Drug Discovery Today 26(4):993-1005. Citation Index: 01, IF: 7.851. Linkhttps://doi.org/10.1016/j.drudis.2020.12.021
  10. Patra, A., Banerjee, D., Dasgupta, S., Mukherjee, A. K.(2021) The invitro laboratory tests and mass spectrometry-assisted quality assessment of commercial polyvalent antivenom raised against the ‘Big Four’venomous snakes of India. Toxicon. 192,15-31. Citation Index: NA, IF: 3.003. Linkhttps://doi.org/10.1016/j.toxicon.2020.12.015
  11. Mukherjee, A. K.(2020). Species-specific and geographical variation in venom composition of two major cobras in Indian subcontinent: Impact on polyvalent antivenom therapy. Toxicon 188, 150-158. Citation Index: NA,  IF: 3.003. Link: https://doi.org/10.1016/j.toxicon.2020.10.024
  12. Puzari, U., Mukherjee, A. K.(2020). Recent developments in diagnostic tools and bioanalytical methods for analysis of snake venom: A critical review. Analytica Chimica Acta 1137, 208-224. Citation Index: 01, IF: 6.558. Linkhttps://doi.org/10.1016/j.aca.2020.07.054
  13. Islam, T., Majumder, M., Kalita, B., Bhattacharjee, A., Mukhopadhyay, R., Mukherjee, A. K.(2020) Transcriptomic, proteomic and biochemical analyses reveal a novel neuritogenesis mechanism of Naja naja venom α-elapitoxin post binding to TrkA receptor of rat pheochromocytoma cells. Journal of Neurochemistry.155, 612–637. Citation Index: NA,  IF: 5.372. Linkhttps://onlinelibrary.wiley.com/doi/epdf/10.1111/jnc.15153
  14. Islam T, Majumdar, M., Bidkar, A., Ghosh, S. S., Mukhopadhyay, R., Utkin, Y.,Mukherjee, A. K. (2020) Nerve growth factor from Indian Russell’s viper venom (RVV-NGFa) shows high affinity binding to TrkA receptor expressed in breast cancer cells: Application of fluorescence labeled RVV-NGFa in the clinical diagnosis of breast cancer. Biochimie 176, 311-44. Citation Index: 01,  IF: 4.079. Linkhttps://doi.org/10.1016/j.biochi.2020.06.004
  15. Chanda, A., Mukherjee, A. K.(2020) Mass spectrometry analysis to unravel the venom proteome composition of Indian snakes: Opening new avenues in clinical research. Expert Review of Proteomics 17:5, 411-423. Citation Index: 02, IF: 3.614. Linkhttps://doi.org/10.1080/14789450.2020.1778471
  16. Patra, A.,Mukherjee, A. K.(2020) Proteomic analysis of Sri Lanka Echis carinatusvenom: Immunological cross-reactivity and enzyme neutralization potency of Indian polyantivenom. Journal of Proteome Research 19, 3022–3032. Citation Index: NA, IF: 4.446. Link: https://doi.org/10.1021/acs.jproteome.0c00054
  17. Chanda, A.,Mukherjee, A. K. (2020) Quantitative proteomics to reveal the composition of Southern India spectacled cobra (Naja naja) venom and its immunological cross-reactivity towards commercial antivenom. International Journal of Biological Macromolecules 160, 224-232. Citation Index: 05, IF: 6.935. Linkhttps://doi.org/10.1016/j.ijbiomac.2020.05.106
  18. Das, B., Patra, A.,Mukherjee, A. K. (2020) Correlation of venom toxinome composition of Indian red scorpion (Mesobuthus tamulus) with clinical manifestations of scorpion sting: Failure of commercial antivenom to immune-recognize the abundant of low molecular mass toxins of this venom. Journal of Proteome Research 19(4),1847-1856. Citation Index: 01, IF: 4.446. DOI1021/acs.jproteome.0c00120
  19. Gogoi, D., Jha,S.,  Chattopadhyay, P.,  Mukherjee, A. K. (2020) A simple, cost-effective, and rapid separation process for the isolation of anticoagulant active fraction from the fruit extract of Momordica charantia: Characterization of bioactive components and anticoagulant mechanism of active fraction in a mouse model. Journal of Separation Science 43, 3902-3912. Citation Index: NA,  IF: 3.645. Link1002/jssc.202000452
  20. Rai, S. K., Roy, J. K., Mukherjee, A. K. (2020) Application of poly(vinyl alcohol) assisted silver nanoparticles immobilized β-keratinase composite as topical antibacterial and dehairing agent. Journal of Protein and Proteomics. 11,119–134. Citation Index: NA,  IF: 2.75. Linkhttps://doi.org/10.1007/s42485-020-00034-x

2018-19

  1. Kalita B,Dutta, S., Mukherjee, A. K. (2019) RGD-independent binding of Russell’s Viper venom Kunitz-type protease inhibitors to platelet GPIIb/IIIa receptor. Scientific Reports 9, 8316. Citation Index: 02, IF: 3.998. DOI1038/s41598-019-44767-2
  1. Kalita B,Mukherjee, A. K. (2019) Recent advances in snake venom proteomics research in India: A new horizon to decipher the geographical variation in venom proteome composition and exploration of candidate drug prototypes. Journal of Proteins and Proteomics 10, 149-164. Citation Index: 05, IF: 2.37. Linkhttps://link.springer.com/article/10.1007/s42485-019-00014-w
  2. Thakur, R., Chattopadhyay, P.,Mukherjee, A. K. (2019) The wound healing potential of a pro-angiogenic peptide purified from Indian Russell’s Viper (Daboia russelii) venom. Toxicon 165, 72-82. Citation Index: 03, IF: 2.27. Link1016/j.toxicon.2019.04.009
  3. Patra, A., Chanda, A., Mukherjee, A. K.(2019) Quantitative proteomic analysis of venom from Southern India common krait (Bungarus caeruleus) and identification of poorly immunogenic toxins by immune-profiling against commercial antivenom. Expert Review of Proteomics 16 (5), 457-469. Citation Index:13,IF: 3.64. Link1080/14789450.2019.1609945
  4. Dutta, S.,Sinha, A., Dasgupta, S., Mukherjee, A. K.(2019) Binding of a Naja naja venom acidic phospholipase Acognate complex to membrane-bound vimentin of rat L6 cells: Implications in cobra venom-induced cytotoxicity. Biochimica et Biophysica Acta-Biomembrane 1861, 958-977. Citation Index: 10 , IF: 3.49. Link :1016/j.bbamem.2019.02.002
  5. Chanda, A., Kalita, B.,Patra, A., D. Sandani T. Senevirathne, Mukherjee, A. K.(2019) Proteomic analysis and antivenomics study of Western India Naja naja venom: Correlation between venom composition and clinical manifestations of cobra bite in this region. Expert Review of Proteomics 16 (2), 171-184. Citation Index:14,IF: 3.64Link1080/14789450.2019.1559735
  6. Gogoi, D., Ramani, S., Bharati, S., Chattopadhyay, P., Mukherjee, A. K. (2019) Characterization of active anticoagulant fraction and a fibrin(ogen)olytic serine protease from leaves of Clerodendrum colebrookianum, a traditional ethno-medicinal plant used to reduce hypertension. Journal of Ethnopharmacology 243, 112099. Citation Index: 4,  IF: 3.69. Link10.1016/j.jep.2019.112099
  7. Chanda, A., Patra, A., Kalita, B.,Mukherjee, A. K. (2018) Proteomics analysis to compare the venom composition between Naja naja and Naja kaouthia from the same geographical location of eastern India: correlation with pathophysiology of envenomation and immunological cross-reactivity towards commercial polyantivenom. Expert Review of Proteomics 15 (11), 949-961. Citation Index: 15, IF: 3.64Link1080/14789450.2018.1538799
  8. Kalita, B., Mackessy, S. P., Mukherjee, A. K.(2018) Proteomic analysis reveals geographic variation in venom composition of Russell’s Viper in the Indian subcontinent: Implications for clinical manifestations post-envenomation and antivenom treatment. Expert Review of Proteomics 15, 837-849. Index: 16, IF: 3.64Link1080/14789450.2018.1528150
  9. Patra, A., Kalita, B.,Mukherjee, A. K.(2018) Assessment of quality, safety, and pre-clinical toxicity of an equine polyvalent anti-snake venom (Pan Africa): Determination of immunological cross-reactivity of antivenom against venom samples of Elapidae and Viperidae snakes of Africa. Toxicon 153, 120-128. Citation Index: 5,IF: 2.27Link1016/j.toxicon.2018.08.018
  10. Kalita, B., Patra, A., Das, A., Mukherjee, A. K.(2018) Proteomic analysis and immuno-profiling of eastern India Russell’s viper (Daboia russelii) venom: Correlation between RVV composition and clinical manifestations post RV bite. Journal of Proteome Research17, 2819–2833. Citation Index: 17, IF: 4.074Link1021/acs.jproteome.8b00291
  11. Kalita, B., Singh, S., Patra, A., Mukherjee, A. K.(2018) Quantitative proteomic analysis and antivenom study revealing that neurotoxic phospholipase A2enzymes, the major toxin class of Russell’s viper venom from southern India, shows the least immuno-recognition and  neutralization by commercial polyvalent antivenom. International Journal of Biological Macromolecules 118, 375-385. Citation Index: 20 , IF:5.162. Link1016/j.ijbiomac.2018.06.083
  12. Mukherjee, A. K., Saviola, A. J., Mackessy, S. P. (2018) Cellular mechanism of resistance of human colorectal adenocarcinoma cells against apoptosis-induction by Russell’s Viper venom L-amino acid oxidase (Rusvinoxidase). Biochimie150, 8-15. Citation Index: 6, IF: 3.41. Link1016/j.biochi.2018.04.017
  13. Kalita, B., Patra, A.,Jahan, S.,Mukherjee, A. K. (2018) First report of the characterization of a snake venom apyrase (Ruviapyrase) from Indian Russell’s viper (Daboia russelii) venom. International Journal of Biological Macromolecules111, 639-648. Citation Index: 3, IF: 5.162. Link1016/j.ijbiomac.2018.01.038
  14. Mackessy, S. P., Saviola, S. P., Mukherjee, A. K.(2018) Venom toxins to drugs: Anti-thrombotic and anti-metastatis compounds from snake venoms. Toxicon150, 320. Citation Index: NA, IF: 2.27Linkhttps://doi.org/10.1016/j.toxicon.2018.06.016
  15. Gogoi, D., Pal, A., Chattopadhyay, P., Pal, S., Deka, R; Mukherjee, A. K. (2018) First report of plant-derived β-sitosterol with antithrombotic, in vivo anticoagulant, and thrombus-preventing activities in a mouse model. Journal of Natural Products 81 (11), 2521-2530. Citation Index:3,  IF: 4.25Link10.1021/acs.jnatprod.8b00574
  16. Gogoi, D., Arora, N., Kalita, B., Sarma, R., Islam, T., Ghosh, S. S., Devi, R., Mukherjee, A. K. (2018) Anticoagulant mechanism, pharmacological activity, and assessment of preclinical safety of a novel fibrin(ogen)olytic serine protease from leaves of Leucas indicaScientific Reports 18;8(1):6210. Citation Index: 9,  IF: 3.998Linkhttps://doi.org/10.1038/s41598-018-24422-y
  17. Bora, B., Gogoi, D.,Tripathy, D.,Kurkalang, S., Ramani, S., Chatterjee, A., Mukherjee, A.K.,  (2018) The N-terminal-truncated recombinant fibrin(ogen)olytic serine protease improves its functional property, demonstrates in vivo anticoagulant and plasma defibrinogenation activity as well as pre-clinical safety in rodent model. International Journal of Biological macromolecules 111, 462-474. Citation Index: 01,  IF: 5.16. Link10.1016/j.ijbiomac.2017.12.140

2016-17

  1. Makarova, Y, V., Shelukhina, I. V., Mukherjee, A. K., Kuznetsov, D.V., Tsetlin, V.I., Utkin, Y. N. (2017) Detection of human neuronal α7 nicotinic acetylcholine receptors by conjugates of snake α-neurotoxin with quantum dots. Doklady Biochemistry and Biophysics 475, 252-255. Citation Index: 01, IF: 0.67. Link1134/S1607672917040032
  1. Thakur, R.,Mukherjee, A. K. (2017) Pathophysiological significance and therapeutic applications of snake venom protease inhibitors. Toxicon 131, 37-47. Citation Index: 13 , IF: 2.27. Link1016/j.toxicon.2017.03.011
  2. Dutta, S., Chanda, A., Kalita, B., Islam, T., Patra, A., Mukherjee, A. K.(2017) Proteomic analysis to unravel the complex venom proteome of eastern India Naja naja: correlation of venom composition with its biochemical and pharmacological properties. Journal of Proteomics 156, 29-39. Citation Index: 54,  IF: 3.66. Linkhttps://doi.org/10.1016/j.jprot.2016.12.018
  3. Kalita, B., Patra, A., Mukherjee, A. K. (2017) Unravelling the proteome composition and immuno-profiling of western India Russell’s Viper venom for in-depth understanding of its pharmacological properties, clinical manifestations, and effective antivenom treatment. Journal of Proteome Research16, 583-598. Citation Index: 42, IF: 4.07. Linkhttps://doi.org/10.1021/acs.jproteome.6b00693
  4. Mukherjee, A. K., Bhagowati, P., Biswa, B.,Chanda, A., Kalita, B. (2017) A comparative intracellular proteomic profiling of Pseudomonas aeruginosa strain ASP-53 grown on pyrene or glucose as sole source of carbon and identification of some key enzymes of pyrene biodegradation pathway. J. Proteomics 167, 25-35. Citation Index: 12,  IF: 3.66. Link10.1016/j.jprot.2017.07.020
  5. Mukherjee, A., Chettri, B., Langpoklakpam, J. S., Basak, P., Prasad, A., Mukherjee, A. K., Bhattacharyya, M., Singh, A. K., Chattopadhyay, D. (2017)  Bioinformatics approaches including predictive metagenomic profiling reveals characteristics of bacterial response to petroleum hydrocarbon contamination in diverse environments. Scientific Reports 7:1108. Citation Index: 64,  IF: 3.998Linkhttps://doi.org/10.1038/s41598-017-01126-3
  6. Bora, B., Biswas, A. D., Gurung, A. B., Bhattacharjee, A., Satish Kuma, M. V., Mukherjee, A. K. (2017) An in silico approach to understand the structure-function properties of a serine protease (Bacifrinase) from Bacillus cereus and experimental evidence to support the interaction of Bacifrinase with fibrinogen and thrombin. Journal of Biomolecular Structure and Dynamics 35 (3) 622-644. Citation Index: 3, IF: 3.22Link1080/07391102.2016.1158665
  7. Patra, A.,Kalita, B., Chanda, A., Mukherjee, A. K. (2017) Proteomics and antivenomics of Echis  carinatus carinatus venom: Correlation with pharmacological properties and pathophysiology of envenomation. Scientific Reports 7, 17119. Citation Index: 40, IF: 3.998. Linkhttps://www.nature.com/articles/s41598-017-17227-y
  8. Thakur, R, Kini, S., Karkulang, S., Banerjee, A., Chatterjee, P., Chanda, A., Chatterjee, A., Panda, D., Mukherjee, A. K.(2016) Mechanism of apoptosis induction in human breast cancer MCF-7 cell by Ruviprase, a small peptide from Daboia russelii russelii. Chemico-Biological Interactions 258, 297-304. Citation Index: 8, IF: 3.45Link1016/j.cbi.2016.09.004
  9. Mukherjee, A.K, Dutta, S., Kalita, B., Jha, D.K., Deb, P., Mackessy, S. P. (2016) Structural and functional characterization of complex formation between two Kunitz-type serine protease inhibitors from Russell’s Viper venom. Biochimie128-12, 138-147. Citation Index: 16, IF: 3.41. Linkhttps://doi.org/10.1016/j.biochi.2016.08.005
  10. Mukherjee, A.K, Kalita, B., Mackessy, S. P. (2016) A proteomics analysis of Pakistan Daboia russelii russeliivenom and assessment of potency of Indian polyvalent and monovalent antivenom. Journal of Proteomics144, 73-86. Citation Index: 45, IF: 3.66. Link1016/j.jprot.2016.06.001
  11. Modahl,C. M.,Mukherjee, A.K., Mackessy, S. P. (2016) An analysis of venom ontogeny and prey-specific toxicity in the Monocled Cobra (Naja kaouthia). Toxicon119, 8-20. Citation Index: 39, IF: 2.27Link1016/j.toxicon.2016.04.049
  12. Saviola, A. J., Burns, P. D.,Mukherjee, A. K., Mackessy, S. P. (2016) The disintegrin Tzabcanin inhibits adhesion and migration in melanoma and lung cancer cells. International Journal of Biological Macromolecules88, 457-464. Citation Index: 24, IF: 5.16. Linkhttps://doi.org/10.1016/j.ijbiomac.2016.04.008
  13. Gogoi, D.,Bhagowati, P., Gogoi, P., Bordoloi, N. K., Rafay, A., Dolui, S. K., Mukherjee, A. K. (2016) Structural and physico-chemical characterization of a dirhamnolipidbio surfactant purified from Pseudomonas aeruginosa: Application of crude biosurfactant in enhanced oil recovery. RSC Advances6, 70669-70681. Citation Index: 23, IF: 3.07. Linkhttps://doi.org/10.1039/C6RA11979D.
  14. Bordoloi, N.K., Bhagowati, P, Chaudhuri, M.K., Mukherjee, A.K. (2016) Proteomics and metabolomics analyses to elucidate the desulfurization pathway of Chelato coccus PLoS One 11, e0153547. Citation Index: 18, IF: 2.74Link10.1371/journal.pone.0153547
  15. Majumdar, S., Chattopadhyay, P., Mukherjee, A. K. (2016) In vivo anticoagulant and thrombolytic activities of a fibrinolytic serine protease (Brevithrombolase) with the k-carrageenan-induced rat tail thrombosis model. Clinical and Applied Thrombosis Hemostasis 22, 594-598. Citation Index: 12,  IF: 1.852.  Link10.1177/1076029615569567

2014-15

  1. Mukherjee, A. K., Saviola, A. J., Burns, P.D., Mackessy, S. P. (2015) Apoptosis induction in human breast cancer (MCF-7) cells by a novel venom L-amino acid oxidase (Rusvinoxidase) is independent of its enzymatic activity and is accompanied by caspase-7 activation and reactive oxygen species production. Apoptosis 20, 1358-1372. Citation Index: 61, IF: 4.54. Link1007/s10495-015-1157-6
  2. Thakur, R, Chattopadhyay D., Ghosh S. S.,Mukherjee, A. K. (2015) Elucidation of procoagulant mechanism and pathophysiological significance of a new prothrombin activating metalloprotease purified from Daboia russelii russelii Toxicon100, 1-12. Citation Index: 20, IF: 2.27. Link1016/j.toxicon.2015.03.019
  3. Dutta, S., Gogoi, D,Mukherjee, A. K. (2015) Anticoagulant mechanism and platelet deaggregation property of a non-cytotoxic, acidic phospholipase A2 purified from Indian cobra (Naja naja) venom: Inhibition of anticoagulant activity by low molecular weight heparin. Biochimie 110, 93-106. Citation Index: 46, IF: 3.41Link1016/j.biochi.2014.12.020
  4. Thakur, R, Chattopadhyay, P.,Mukherjee, A. K. (2015) Biochemical and pharmacological characterization of a toxic fraction and its cytotoxin-like component isolated from Russell’s Viper (Daboia russelii russelii) venom. Comparative Biochemistry and Physiology C 168, 55-65. Citation Index: 13, IF: 2.89Link1016/j.cbpc.2014.12.001
  5. Roy, J.K., Manhar, A. K., Nath, D., Mandal, M., Mukherjee, A. K. (2015) Cloning and extracellular expression of a raw starch digesting a-amylase (Blamy-I) and its application in bioethanol production from a non-conventional source of starch. Journal of Basic Microbiology 55, 1287–1298. Citation Index: 6,  IF: 1.79Link10.1002/jobm.201400949
  6. Rai, S. K., Mukherjee, A. K. (2015) Optimization for production of liquid nitrogen fertilizer from the degradation of chicken feather by iron-oxide (Fe3O4) magnetic nanoparticles coupled β-keratinase. Biocatalysis and Agricultural Biotechnology 4, 632-634. Citation Index: 14,  IF: 2.6Linkhttps://doi.org/10.1016/j.bcab.2015.07.002
  7. Majumdar, S., Dutta, S., Das, T., Chattopadhyay, P., Mukherjee, A. K. (2015) Antiplatelet and antithrombotic activity of a fibrin(ogen)olytic protease from Bacillus cereus strain FF01. International Journal of Biological Macromolecules 79, 477-489. Citation Index: 12,  IF: 5.16Link10.1016/j.ijbiomac.2015.04.075
  8. Majumdar, S., Goswami, S., Keppen, C., Rai, S. K., Mukherjee, A. K. (2015) Statistical optimization for improved production of fibrin(ogen)olytic enzyme by Bacillus cereus strain FF01 and its in vitro thrombolytic potential of protease enzyme. Biocatalysis and Agricultural Biotechnology 4, 191-198. Citation Index: 09,  IF: 2.6. Linkhttps://doi.org/10.1016/j.bcab.2014.11.004
  9. Mukherjee, A. K., Dutta, S., Mackessy, S. P. (2014) A new C-type lectin (RVsnaclec) purified from venom of Daboia russelii russelii shows anticoagulant activity via inhibition of FXa and concentration-dependent differential response to platelets in a Ca2+-independent  manner. Thrombosis Research134, 1150-1156. Citation Index: 30, IF: 2.77.  Link1016/j.thromres.2014.09.009
  10. Thakur, R., Kumar A., Bose B., Panda D., Saikia D, Chattopadhyay P, Mukherjee A. K. (2014) A new peptide (Ruviprase) purified from the venom of Daboia russelii russelii shows potent anticoagulant activity via non-enzymatic inhibition of thrombin and factor Xa. Biochimie105, 149-158. Citation Index: 31, IF: 3.41Link1016/j.biochi.2014.07.006
  11. Kalita, D., Saikia, J.,Mukherjee, A. K., Doley, R. (2014) Anethnomedicinal survey of traditionally used medicinal plants for the treatment of snakebite in Morigaon district of Assam, India. International Journal of Medicinal and Aromatic Plants4, 97-102. Citation Index: NA, IF: NALink: NA
  12. Mukherjee, A. K., Mackessy, S. P. (2014) Pharmacological properties and pathophysiological significance of a Kunitz-type protease inhibitor (Rusvikunin-II) and its protein complex (Rusvikunin complex) purified from Daboia russelii russeliiToxicon89, 55-66. Citation Index: 35, IF: 2.27. Linkhttps://doi.org/10.1016/j.toxicon.2014.06.016
  13. Mukherjee, A. K., Kalita, B., Thakur, R. (2014) Two acidic, anticoagulant PLA2isoenzymes purified from the venom of monocled cobra Naja kaouthiaexhibit different potency to inhibit thrombin and factor Xa via phospholipids independent, non-enzymatic mechanism. PLoS One 9(8), e101334. Citation Index: 24, IF: 2.74. Linkhttps://doi.org/10.1371/journal.pone.0101334.
  14. Mukherjee, A. K., Mackessy, S. P., Dutta, S. (2014) Characterization of a Kunitz-type protease inhibitor peptide (Rusvikunin) purified from Daboia russelii russeliiInternational Journal of Biological Macromolecules67, 154-162. Citation Index: 42, IF: 5.16. Linkhttps://doi.org/10.1016/j.ijbiomac.2014.02.058
  15. Mukherjee, A. K.(2014) The pro-coagulant fibrinogenolytic serine protease isoenzymes from Daboia russelii russeliivenom coagulate the blood through factor V activation: Role of glycosylation on enzymatic activity. PLoS One 9(2): e86823. Citation Index: 40, IF: 2.74. Link:https://doi.org/10.1371/journal.pone.0086823
  16. Mukherjee, A. K. (2014) A major phospholipase Afrom Daboia russelli russelii venom shows potent anticoagulant action via thrombin inhibition and binding with plasma phospholipids. Biochimie99, 153-161. Citation Index: 26, IF: 3.41Link1016/j.biochi.2013.11.026
  17. Mukherjee, A. K., Chatterjee, S., Majumdar, S., Saikia, D., Thakur, R., Chatterjee, A. (2014) Characterization of a pro-angiogenic, novel peptide from Russell’s viper (Daboia russelii russelii) venom. Toxicon77, 26–31. Citation Index: 13, IF: 2.27Link1016/j.toxicon.2013.10.024
  18. Biswas, K., Roy, J. K., Doley, R., Mohanta, D., Mukherjee, A. K. (2014) Imaging bactericidal effect of faceted Ag nanostructures (FAgN) on Gram negative, Coli Form Escherichia coli bacteria. Journal of Bionanoscience 8, 248-254. Citation Index: 03,  IF: 2.8. Linkhttps://doi.org/10.1166/jbns.2014.1230
  19. Majumdar, S., Sarmah, B., Gogoi, D., Banerjee, S., Ghosh, S. S., Banerjee, S., Chattopadhyay, P., Mukherjee, A. K. (2014) Characterization, mechanism of anticoagulant action, and assessment of therapeutic potential of a fibrinolytic serine protease (Brevithrombolase) purified from Brevibacillus brevis strain FF02B. Biochimie 103, 50-60. Citation Index: 36,  IF: 3.41. Link10.1016/j.biochi.2014.04.002
  20. Bordoloi, N. K., Rai, S. K., Chaudhuri, M. K., Mukherjee, A. K. (2014) Deep-desulfurization of dibenzothiophene and its derivatives present in diesel oil by a newly isolated bacterium Achromo bacter sp. to reduce the environmental pollution from fossil fuel combustion. Fuel Processing Technology 119, 236-244. Citation Index: 53,  IF: 4.88. Linkhttps://doi.org/10.1016/j.fuproc.2013.10.014

2012-13

  1. Saikia, D., Majumdar, S., Mukherjee, A. K. (2013) Mechanism of in vivo anticoagulant and haemolytic activity by a neutral phospholipase A2 purified from Daboia russelii russelii venom: Correlation with clinical manifestations in Russell’s Viper envenomed patients.Toxicon 76, 291-300. Citation Index: 22, IF: 2.27Linkhttps://doi.org/10.1016/j.toxicon.2013.10.001
  2. Mukherjee, A. K., Mackessy, S. P. (2013) Biochemical and pharmacological properties of a new thrombin-like serine protease (Russelobin) from the venom of Russell’s Viper (Daboia russelii russelii) and assessment of its therapeutic potential. Biochimica et Biophysica Acta –General Subjects 1830, 3476-3488. Citation Index: 80, IF: 3.51. Linkhttps://doi.org/10.1016/j.bbagen.2013.02.007
  3. Roy, J. K., Mukherjee, A. K. (2013) Applications  of  a  high  maltose  forming,  thermo-stable  α- amylase from an  extremely  alkalophilic Bacillus  licheniformis strain  AS08E  in food  and Laundry detergent  industries. Biochemical Engineering Journal 77, 220-230. Citation Index: 46 ,  IF: 3.47Linkhttps://doi.org/10.1016/j.bej.2013.06.012
  4. Roy, J. K., Borah, A., Mahanta, C. L., Mukherjee, A. K. (2013) Cloning and overexpression of raw starch digesting α-amylase gene from Bacillus subtilis strain AS01a in Escherichia coli and application of the purified recombinant α-amylase (AmyBS-I)   in raw starch digestion and baking industry. J. Molecular. Catalysis B: Enzymatic 97,118-129. Citation Index: 28,  IF: 2.53. Linkhttps://doi.org/10.1016/j.molcatb.2013.07.019
  5. Saikia, D., Bordoloi, N. K., Chattopadhyay, P., Chocklingam, S., Ghosh, S. S., Mukherjee, A. K. (2012) Differential mode of attack on membrane phospholipids by an acidic phospholipase A2(RVVA-PLA2-I) from Daboia russelli. Biochemica et Biophysica Acta –Biomembrane 12, 3149-3157. Citation Index: 39, IF: 3.45Linkhttps://doi.org/10.1016/j.bbamem.2012.08.005
  6. Mukherjee, A. K., Mackessy, S. P. (2012) Russelobin, a non-toxic thrombin-like serine protease from the venom of Russell’s viper (Daboia russelli russelli): Possible applications in cardiovascular drug development. Toxicon 60, 109-110. Citation Index: NA , IF: 3.035 Linkhttps://doi.org/10.1016/j.toxicon.2012.04.030
  7. Mukherjee, A. K. (2012) Green medicine as a harmonizing tool to antivenom therapy for the clinical management of snakebite: the road ahead. Indian Journal of Medical Research 136, 10-12. Citation Index: 25, IF:1.50. Linkhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461710/
  8. Nair, R. G., Roy, J. K., Samdarshi, S. K.  Mukherjee, A. K. (2012) Mixed phase V doped titania shows high photoactivity for disinfection of Escherichia coli and detoxification of phenol. Solar Energy Materials and Solar Cells 105, 103-108. Citation Index: 28,  IF: 6.98. Linkhttps://doi.org/10.1016/j.solmat.2012.05.008
  9. Mukherjee, A. K., Bordoloi, N. K. (2012) Biodegradation of benzene, toluene and xylene (BTX) in liquid culture and in soil by Bacillus subtilis and Pseudomonas aeruginosa strains and a formulated bacterial consortium. J  Environmental Science and Pollution Research 19, 3380–3388. Citation Index: 85,  IF: 3.2Link10.1007/s11356-012-0862-8
  10. Mukherjee, A. K., Rai, S. K., Thakur, R., Chattopadhyay, P., Kar, S. K. (2012) Bafibrinase: A non-toxic, non-hemorrhagic, direct-acting fibrinolytic serine protease from Bacillus sp. strain AS- S20-I exhibits in vivo anticoagulant activity and thrombolytic potency. Biochimie 94, 1300-308. Citation Index: 64,  IF: 3.41Link10.1016/j.biochi.2012.02.027
  11. Das, G., Bordoloi, N. K., Rai, S. K., Mukherjee, A. K., Karak, N. (2012) Biodegradable and biocompatible epoxidized vegetable oil modified   thermostable poly (vinyl chloride): Thermal and performance characteristics post biodegradation with Pseudomonas aeruginosa and  Achromobacter sp. Journal of  Hazardous Materials 209 -210, 434 - 442. Citation Index: 20,  IF: 8.2Link10.1016/j.jhazmat.2012.01.043
  12. Roy, J. K., Rai, S. K., Mukherjee, A. K. (2012) Characterization and application of a detergent-stable α-amylase from Bacillus subtilis AS‑S01a. International Journal of Biological Macromolecules 50, 219-229. Citation Index: 54,  IF: 5.16. Link10.1016/j.ijbiomac.2011.10.026
  13. Das, G., Roy, J., Mukherjee, A. K., Karak, N. (2012) Mesua ferrea L. seed oil modified sulfone epoxy resin and multi-walled carbon nanotube nanocomposites and their biomedical and mechanical properties. Advanced Science Letters 4, 1-9. Citation Index: NA,  IF: 0.4. Link10.1166/asl.2012.2022

 2010-11

  1. Saikia D., Thakur, R., Mukherjee, A. K. (2011) An acidic phospholipase A2 (RVVA-PLA2-I) purified from Daboia russelli venom exerts its anticoagulant activity by enzymatic hydrolysis of plasma phospholipids and by non-enzymatic inhibition of factor Xa in a phospholipids/Ca2+ independent manner. Toxicon 57841-850. Citation Index: 46 , IF: 2.27. Linkhttps://doi.org/10.1016/j.toxicon.2011.02.018
  2. Mukherjee, A. K., Saikia, D., Thakur, R. (2011) Medical and diagnostic application of snake venom proteomes. Proteins and Proteomics2(1), 31-40. Citation Index: NA, IF: 2.53. Linkhttps://www.researchgate.net/publication/242331580_Medical_and_diagnostic_applications_of_snake_venom_proteomes
  3. Mukherjee, A. K., Rai, S. K., Bordoloi, N. K. (2011) Biodegradation of waste chicken-feathers by  an alkaline β-keratinase (Mukartinase) purified from a mutant Brevibacillus sp. strain AS-S10-II. International Biodeterioration and Biodegradation 65, 1229-1237. Citation Index: 29,  IF: 4.4Linkhttps://doi.org/10.1016/j.ibiod.2011.09.007
  4. Rai, S. K., Mukherjee, A. K. (2011) Optimization of production of an oxidant and detergent-stable alkaline β-keratinase from Brevibacillus sp. strain AS-S10-II: application of enzyme in laundry detergent formulations and in leather industry. Biochemical Engineering Journal 54, 47-56. Citation Index: 63,  IF: 3.47Linkhttps://doi.org/10.1016/j.bej.2011.01.007
  5. Nair, R. G., Roy, J. K., Samdarshi, S. K., Mukherjee, A. K. (2011) Enhanced visible light photocatalytic disinfection of gram negative, pathogenic Escherichia coli bacteria with Ag/ TiVoxide nanoparticle. Colloids and Surface B: Biointerfaces 86, 7-13. Citation Index: 20,  IF: 3.99Link10.1016/j.colsurfb.2011.03.011
  6. Mukherjee, A. K., Rai, S. K. (2011) A Statistical approach for the enhanced production of alkaline protease showing fibrinolytic activity from a newly isolated Gram-negative Bacillus sp. strain AS- S20-I. New Biotechnology 28, 182-189. Citation Index: 78,  IF: 4.45. Link10.1016/j.nbt.2010.11.003
  7. Mukherjee, A. K., Bordoloi, N. K. (2011) Bioremediation and reclamation of soil contaminated with petroleum - oil hydrocarbons by exogenously seeded bacterial consortium: a pilot scale study. Environmental Science and Pollution Research International 18, 471-478. Citation Index: 77,  IF: 3.2Link10.1007/s11356-010-0391-2
  8. Mukherjee, A. K. (2010) Non-covalent interaction of phospholipase A2(PLA2) and kaouthiotoxin (KTX) from venom of Naja kaouthia exhibits marked synergism to potentiate their cytotoxicity on target cells. Journal of Venom Research 1, 37-42. Citation Index: 30, IF: NA Linkhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086192/
  9. Mukherjee, A. K., Das, K. (2010). Microbial surfactants and their potential applications: an overview. AdvExp Med Biol. 672, 54-64. Citation Index: 68,  IF: 2.45. Link10.1007/978-1-4419-5979-9_4
  10. Mukherjee, A. K., Kumar, T. S., Rai S. K., Roy, J. K. (2010) Statistical optimization of Bacillus alcalophilus α-amylase immobilization onto iron-oxide (Fe3O4) magnetic nanoparticles. Biotechnology and Bioprocess Engineering 15, 984-992. Citation Index:33,  IF: 2.21. Linkhttps://doi.org/10.1007/s12257-009-3160-7
  11. Rai, S. K., Mukherjee, A. K. (2010) Statistical optimization of production, purification and industrial application of a laundry detergent and organic solvent-stable subtilisin like serine protease (Alzwiprase) from Bacillus subtilis DM-04.  Biochemical Engineering Journal 48, 173-178. Citation Index: 120,  IF: 3.47Linkhttps://doi.org/10.1016/j.bej.2009.09.007
  12. Rai, S. K., Roy, J. K., Mukherjee, A. K. (2010) Characterization of a detergent-stable alkaline protease from a novel thermophilic strain Paenibacillus tezpurensis sp.  nov. AS-S24-II. Applied Microbiology and Biotechnology 85, 1437-1450. Citation Index: 77,  IF: 3.53. Link10.1007/s00253-009-2145-y
  13. Mukherjee, A. K., Kalita P., Unni, B. G., Wann, S. B., Saikia, D., Mukhopadhyay, P. K. (2010) Fatty acid composition of four potential aquatic weeds and their possible use as fish-feed neutraceuticals. Food Chemistry 123, 1252-1254. Citation Index: 26,  IF: 6.30. Linkhttps://doi.org/10.1016/j.foodchem.2010.05.057

 2008-09

  1. Mukherjee, A. K., Bordoloi, N. (2009) Microbial biodegradation of petroleum hydrocarbons: towards a safer and cleaner environment. In: proceedings of the International Symposium on Environmental Pollution, Ecology and Human Health, (ISEPEHH-2009), Department of Zoology, S.V. University, India, pp:31-34. Citation Index: NA,  IF: NALink: NA
  2. Rai, S. K., Konwarh, R., Mukherjee, A. K. (2009) Purification, Characterization and biotechnological application of an alkaline β-keratinase produced by Bacillus subtilis RM-01 in solid state fermentation using chicken-feather as substrate. Biochemical Engineering Journal 45, 218-225. Citation Index: 92,  IF:3.47. Linkhttps://doi.org/10.1016/j.bej.2009.04.001
  3. Konwarh, R., Karak, N., Rai, S. K., Mukherjee, A. K (2009) Polymer assisted iron oxide magnetic nanoparticles immobilized keratinase. Nanotechnology Journal, 20, 225107. Citation Index: 115,  IF: 3.55Link10.1088/0957-4484/20/22/225107
  4. Rai, S. K., Mukherjee, A. K. (2009) Ecological significance and some biotechnological application of an organic solvent stable alkaline serine protease from Bacillus subtilis strain DM-04. Bioresource Technology 100, 2642-2645. Citation Index: 69,  IF: 7.53. Linkhttps://doi.org/10.1016/j.biortech.2008.11.042
  5. Mukherjee, A. K., Bora, M., Rai, S. K. (2009)  To study the influence of different components of fermentable substrates on induction of extracellular α-amylase synthesis by Bacillus subtilis DM-03 in solid state fermentation and exploration of feasibility for inclusion of α-amylase in laundry detergent formulations. Biochemical Engineering Journal 43,149-156. Citation Index: 110,  IF: 3.47Linkhttps://doi.org/10.1016/j.bej.2008.09.011
  6. Mukherjee, A. K., Doley, R., Saikia, D. (2008) Isolation of a snake venoms phospholipase A2(PLA2) inhibitor (AIPLAI) from leaves of Azadirachta indica (Neem): mechanism of PLA2 inhibition by AIPLAI in vitro Toxicon 51, 1548-1553. Citation Index: 76, IF: 2.27. Link1016/j.toxicon.2008.03.021
  7. Mukherjee, A. K. (2008) Phospholipase A2-interacting weak neurotoxins from venom of monocled cobra Naja kaouthiadisplay cell specific cytotoxicity.  Toxicon 51, 1538-1543. Citation Index: 18,  IF: 2.27Linkhttps://doi.org/10.1016/j.toxicon.2008.03.014
  8. Mukherjee, A. K. (2008) Characterization of a novel pro-coagulant metalloprotease (RVBCMP) possessing α-fibrinogenase and tissue hemorrhagic activity from venom of Daboia russelli russelli (Russell's Viper): evidence of distinct coagulant and hemorrhagic sites in RVBCMP. Toxicon51, 923-933. Citation Index: 53,  IF: 2.27Link1016/j.toxicon.2007.12.008
  9. Mukherjee, A. K., Adhikary, H., Rai, S. K. (2008) Production of alkaline protease by a thermophilicBacillus subtilis under solid state fermentation (SSF) condition using Imperata cylindrica grass and potato peel as low cost medium: Characterization and application of enzyme in detergent formulation. Biochemical Engineering Journal  39, 353-361. Citation Index: 195,  IF: 3.47Linkhttps://doi.org/10.1016/j.bej.2007.09.017
  10. Kalita, P., Mukhopadhyay, P.K., Mukherjee, A.K. (2008) Supplementation of four non-conventional aquatic weeds to the basal diet of Catla catla (Ham.) and Cirrhinus mrigala (Ham.) fingerlings: Effect on growth, protein utilization and body composition of fish. Acta Ichthyologica et Piscatoria 38, 21-27. Citation Index: 22,  IF: 0.67Link10.3750/AIP2008.38.1.03

2006-07

  1. Mukherjee, A. K. (2007) Correlation between the phospholipids domains of the target cell membrane and the extent of Naja kaouthia PLA-induced membrane damage: Evidence of distinct catalytic and cytotoxic sites in PLABiochemica et Biophysica Acta 1770, 187-195. Citation Index: 45, IF: 3.67Linkhttps://doi.org/10.1016/j.bbagen.2006.09.021
  2. Das, K., Mukherjee, A.K. (2007) Comparison of lipopeptidebiosurfactants production by Bacillus subtilis strains in submerged and solid state fermentation systems using a cheap carbon source: some industrial application of biosurfactants.  Process Biochemistry 42, 1191-1199. Citation Index: 205,  IF: 3.2Linkhttps://doi.org/10.1016/j.procbio.2007.05.011
  3. Mukherjee, A. K. (2007) Potential application of cyclic lipopeptide (CLP) biosurfactants produced by Bacillus subtilis strains in laundry detergent formulations. Letters in Applied Microbiology 45, 330-335. Citation Index: 69,  IF: 1.89. Link10.1111/j.1472-765X.2007.02197.x
  4. Das, K., Mukherjee, A. K. (2007) Differential utilization of pyrene as sole source of carbon by Bacillus subtilis and Pseudomonas aeruginosa strains: Role of biosurfactants in enhancing the bioavailability. Journal of Applied Microbiology  102, 195-203. Citation Index: 121,  IF: 3.06. Link10.1111/j.1365-2672.2006.03070.x
  5. Kalita, P., Mukhopadhyay, P. K., Mukherjee, A. K. (2007) Evaluation of the nutritional quality of four unexplored aquatic weeds from North East India for the formulation of cost-effective fish feeds. Food Chemistry  103, 204-209. Citation Index: 77,  IF: 6.30. Linkhttps://doi.org/10.1016/j.foodchem.2006.08.007
  6. Das, K., Mukherjee, A. K. (2007) Crude petroleum-oil biodegradation efficiency of Bacillus subtilis and Pseudomonas aeruginosa strains isolated from petroleum oil contaminated soil from North-East India. Bioresource Technology 98, 1339-1345. Citation Index: 706,  IF: 7.53. Linkhttps://doi.org/10.1016/j.biortech.2006.05.032
  7. Mukherjee, A. K., Sollod, B. L., Wikel, S. K., King, G. F. (2006) Orally active acaricidal peptide toxins from the venom of the Australian funnel-web spider. Toxicon 47, 182-187. Citation Index: 50, IF: 2.27Link1016/j.toxicon.2005.10.011
  8. Das, K., Mukherjee, A. K. (2006) Assessment of mosquito larvicidal potency of cyclic lipopeptides produced by Bacillus subtilis strains. Acta Tropica  97, 168-173. Citation Index: 64,  IF: 2.65Link10.1016/j.actatropica.2005.10.002

2004-05

  1. Das, K., Mukherjee, A. K. (2005) Characterization of biochemical properties and biological activities of biosurfactants produced by Pseudomonas aeruginosa mucoid and non-mucoid strains isolated from hydrocarbon-contaminated soil samples. Applied Microbiology and Biotechnology 69, 192-195. Citation Index: 113,  IF: 3.53Link10.1007/s00253-005-1975-5
  2. Mukherjee, A. K., Das, K. (2005) Correlation between diverse cyclic lipopeptides production and regulation of growth and substrate utilization by Bacillus subtilis strains in a particular habitat. FEMS Microbiology Ecology 54, 479-489. Citation Index: 136,  IF: 3.67. Link10.1016/j.femsec.2005.06.003
  3. Doley, R., King, G. F.,Mukherjee, A. K. (2004) Differential hydrolysis of erythrocytes and mitochondrial membrane phospholipids by two phospholipase Aisoenzymes (NK-PLA2-I and NK-PLA2-II) from the venom of the Indian monocled cobra Naja kaouthiaArchives of Biochemistry and Biophysics  425, 1-13. Citation Index: 46, IF: 3.01. Link1016/j.abb.2004.02.007
  4. Das, K., Doley, R., Mukherjee, A. K. (2004) Purification and biochemical characterization of a thermostable, alkaliphilic, extracellular a-amylase from Bacillus subtilis DM-03, isolated from the traditional fermented food of India. Journal of Biotechnology and Applied Biochemistry 40, 291-298. Citation Index:87,  IF: 1.63Link10.1042/BA20040034

2002-03

  1. Doley, R., Mukherjee, A. K. (2003) Purification and characterization of an anticoagulant phospholipase A2 from Indian monocled cobra (Naja kaouthia) venom. Toxicon 41, 81-91. Citation Index: 76 , IF: 2.27Linkhttps://doi.org/10.1016/S0041-0101(02)00213-1
  2. Mukherjee, A. K., Maity, C.R. (2002) Biochemical composition, lethality and pathophysiology of venom from two cobras-Naja najaand kaouthiaComparative Biochemistry and Physiology 131 (B), 125-132. Citation Index: 89, IF: 2.06Linkhttps://doi.org/10.1016/S1096-4959(01)00473-0

2000-2001

  1. Mahanta, M., Mukherjee, A. K. (2001) Neutralization of lethality, myotoxicity and toxic enzymes of Naja kaouthia venom by Mimosa pudica root extracts. Journal of Ethnopharmacology 75, 55-60. Citation Index: 134, IF: 3.7Link1016/s0378-8741(00)00373-1
  2. Mukherjee, A. K., Ghosal, S. K., Maity, C. R. (2000) Some biochemical properties of Russell’s viper (Daboia russelli) venom from eastern India: correlation with clinico-pathological manifestation in Russell’s viper bite. Toxicon 38, 163-175. Citation Index: 64, IF: 2.27. Link1016/s0041-0101(99)00125-7

 1998-99

  1. Mukherjee, A. K., Ghosal, S. K., Maity, C.R. (1998) Effect of dietary supplementation of vitamin E in partial inhibition of Russell’s viper venom phospholipase A2induced hepatocellular and microsomal membrane damage in rats. Acta Physiologica Hungarica 85, 367-374. Citation Index: 18, IF: NALinkhttps://pubmed.ncbi.nlm.nih.gov/10431608/
  2. Mukherjee, A. K., Ghosal, S.K., Maity, C.R. (1998) Effect of oral supplementation of vitamin E on the hemolysis and erythrocyte phospholipids splitting action of cobra and viper venoms. Toxicon 36, 657-664. Citation Index: 22 , IF: 2.27Link1016/s0041-0101(97)00055-x
  3. Mukherjee, A. K., Maity, C. R. (1998) The composition of Naja najavenom samples from three districts of West Bengal, eastern India. Comparative Biochemistry and Physiology 119A, 621-627. Citation Index: 71, IF: 1.96Link1016/s1095-6433(97)00475-3
  4. Mukherjee, A. K., Maity, C. R. (1998). Some biochemical properties of Naja najavenom from Burdwan district of West Bengal, and its biological effects on different organs of rats. Indian Journal of Medical Biochemistry 2, 4-18. Citation Index: NA, IF: 2.67Link: NA

1996-97

  1. Mukherjee, A. K., Ghosal, S. K. and Maity, C. R. (1997) Lysosomal membrane stabilization by alpha –tocopherol against the damaging action of Vipera russellivenom phospholipase A2Cellular and Molecular Life Sciences 53, 152-155. Citation Index: 60, IF: 6.49. Link1007/pl00000586
  1. Publication of General/Review Research Articles:
  1. Thakur, R., Mukherjee, A. K. (2012) Focusing on an emergent class of venom component-Thrombin inhibitors: a potential lead compound for cardiovascular drug development. TSI Newsletter 2 (1), 22-24.
  2. Thakur, R., Mukherjee, A. K. (2011) Venom Therapeutics: A breakthrough in the field of medicine. TSI Newsletter1, 8-10.
  3. Rai S.K., Saikia, D. and Mukherjee, A. K. (2007) Application of enzymes and microbes as molecular recognition elements (MREs) in Biosensors. In: Proceedings of Seminar on Bioelectronics, (Ed., Drs J. C. Dutta and R. Chutia), Bioelectronics Division, Dept. of Electronics and Communication Engineering, Tezpur University, Tezpur, pp: 55-56.
  4. Kalita P., Tag, H., Mukhopadhyay, P. K., Das, A. K. and Mukherjee, A. K. (2005) Indigenous fishing techniques practiced by the tribes of Arunachal Pradesh (north east India). Aquaculture Asia 2, 35-37 (Published from Aquaculture society of Asia, Bangkok, Thailand).
  5. Mukherjee, A. K., Maity, C.R., Bhattacharyya, B (1995) G Proteins-intermediate in signal transduction: a tribute to Rodbell and Gilman. In: Proceedings of the IV the National Conference of the Association of Medical Biochemists of India, (Ed., Prof. C.R. Maity), BurdwanUniversity, Burdwan, pp: 77-84.
  6. Mukherjee, A. K (1994) Oncogene targeted antisense oligonucleotides-a novel approach to the problem of oncogenesis. Everyman's Science XXIX, 106-108.

III. Publication of Book Chapters:

  1. Mukherjee, A. K. (2000) Biotechnology in health care: challenges and promises for us in the next millennium. In: Indian Chemical Industry-Opportunities Unlimited. Published by Dept. of Chemicals and Petrochemicals, Govt. of India, pp: 173-176.
  2. Doley, R., Mukherjee, A. K. (2003)`Pharmacological assessment of medicinal plants to ascertain their anti-snake venom activity. In: Ethnomedicine of North-East India: Protection, Utilization and Conservation. (Singh, G, Singh, H.B. and Mukherjee, T.K. Editors), National Institute of Science Communication and Information Resources, CSIR, New Delhi, pp: 300-304.
  3. Mukherjee, A. K., Das, K. (2010) Microbial Surfactants and their Potential Applications: An Overview. In: Biosurfactants(Sen, R. K., Editor), Landes Bioscience, Texas, USA., pp: 54-64
  4. Mukherjee, A. K. (2013) An updated inventory on properties, pathophysiology and therapeutic potential of snake venom thrombin-like proteases. In: S. Chakraborti, N.S. Dhalla, (Eds.), Proteases in Health and Disease-Advances in Biochemistry in Health and DiseaseVolume 7 (ISBN 978-1-4614-9233-7), Springer, pp.163-180.
  5. Thakur, R., Mukherjee, A. K. (2016) Pathophysiological significance and therapeutic implications of Russell’s Viper venom proteins and peptides affecting blood coagulation. In:Snake Venoms and Envenomation: Modern Trends and Future Prospects, Utkin, Y.N., krivoshein, A.V., Ed; Nova Science Publishers: New York, 2016; pp: 93-114.
  6. Saikia, S., Mukherjee, A. K. (2017) Anticoagulant and membrane damaging properties of snake venom phospholipase A2 enzymes. In: Handbook of Toxinology, volume – snake venom, (Gopalakrishnakone, P., Inagaki, H., Mukherjee, A.K., Rahmy, T.R., Vogel, C.W., Eds); Springer Nature: Netherlands, DOI 10.1007/978-94-007-6648-8_18-1, pp: 87-104
  7. Thakur R, and Mukherjee, A. K. (2017) A Brief Appraisal on Russell’s Viper Venom (Daboia russelii) Proteinases. In: Handbook of Toxinology, volume– snake venom, (Gopalakrishnakone, P., Inagaki, H., Mukherjee, A.K., Rahmy, T.R., Vogel, C.W., Eds); Springer Nature: Netherlands, DOI 10.1007/978-94-007-6648-8_18-1, pp: 123-144
  8. Y. N. Utkin, I. Y. Cherepakhin, E. V. Kryukova, I. V. Shelukhina, Y. V. Makarova, I. E. Kasheverov, A. K. Mukherjee, A. A. Gusev, D. V. Kuznetsov (2017). Conjugates of α-Cobratoxin with CdSe Quantum Dots: Preparation and Biological Activity. In: Nano Hybrids and Composites (A. Gusev, T. Dyatcheck and A.Godymchuk, Eds), Vol. 13, pp. 3-8, DOI: 10.4028/www.scientific.net/NHC.13.3 (online book chapter).
  9. Mukherjee, A. K.,Kalita, B., Dutta, S., Patra, A., Maity, C.R., Punde D. (2020). Snake Envenomation: Therapy and Challenges in India. In: Section V: Global Approaches to Envenomation and Treatments, Handbook of Venoms and Toxins of Reptiles, Second Edition (S. P. Mackessy, Editor), CRC Press, USA (accepted manuscript in press).
  1. List of International Patents Applied/Granted:
  1. US patent on "Acaricidal compositions and methods of use thereof". United States patent No.: US 7,575,758 B2; filing date: 13.09.2006; Publication date: August 2009
  2. International patent on "Acaricidal compositions and methods of use thereof". International patent publication No. WO/2007/035382, dated 29 March, 2007
  3. PCT International patent on “ANTICOAGULANT ACTIVES AND SYNERGISTIC ANTICOAGULANT COMPOSITION AND METHOD FOR PRODUCING THE SAME". Publication Number: WO/2017/103949; Publication Date: 22.06.2017. International Application No.PCT/IN2016/050448
  1. Indian Patents Filed:
  1. Indian Patenton “ANTICOAGULANT ACTIVES AND SYNERGISTIC ANTICOAGULANT COMPOSITION AND METHOD FOR PRODUCING THE SAME” PATENT NO. 1313/KOL/2015; Date of publication 01.12.2017, Granted on 30/03/2023.
  2. Indian Patent on “SYNTHETIC ANTICOAGULANT PEPTIDES DERIVED FROM NAJA NAJA SNAKE VENOM”PATENT APPLICATION NO. 201831010001; Complete specification filing date: 15 March, 2019
  3. Indian Patent on “TOXIN EPITOPE-BASED DETECTION OF SPECIES-SPECIFIC SNAKE ENVENOMATION”PATENT APPLICATION NO. 201831010002; Complete specification filing date: 18 October 2019; Publication date 20.3.2020
  4. Indian Patent on “TOXINS-TARGETED SPECIFIC NOVEL ANTI SNAKE VENOM”PATENT APPLICATION NO.201831038837, Filing date: 5 October, 2019
  5. Indian Patent on   “CUSTOM SYNTHESIZED NERITOGENIC PEPTIES AND ITS USES THEROF” PATENT APPLICATION NO.201931052903, provisional filing date: 19 December, 2019

Research Projects Ongoing:

Sl. No.

Duration

Project Title

Sponsoring agency

Fund sanctioned (Rupess)

1.

April 2023

Mar 2025

Studies on the potency of natural and synthetic compounds as antidotes for neurotoxic snake and scorpion venoms

IASST In-house Core Grant, Guwahati, Assam, India

12,00,000.00

2.

April 2023

Mar 2025

Studies on the neuroprotective potential of natural and synthetic compounds

IASST In-house Core Grant, Guwahati, Assam, India

13,00,000.00

3.

May 2023

Apr 2024

Proteomic and structural analysis of cypoviral protein from infected Muga silkworm [Antheraea assamensis Helfer (Lepidoptera: Saturnidae)] and suppression of disease by chemical and biological agents

IASST In-house Core Grant, Guwahati, Assam, India

3,00,000.00

Research Projects Completed:

Sl. No.

Duration

Project Title

Sponsoring agency

Fund sanctioned (Rupess)

1.

Apr 2021

Mar 2023

Phytochemical characterization, assessment of storage stability, and biomedical application of some edible mushrooms grown in Assam, North –East India

IASST In-house Core Grant, Guwahati, Assam, India

24,00,000.00

2.

Dec 2018

Dec 2022

Studies on signal transduction mechanism(s) of neurotrophin molecules from Indian cobra (Naja naja) and Russell’s Viper (Daboia russelii) venoms in cultured neuronal cells and their functional significance

SERB, New Delhi

39,29.600.00

3.

Apr 2019

Apr 2021

Studies on country specific polyvalent Snake Venom Antiserum for Sri Lanka developed by Premium Serums & Vaccines Pvt. Ltd: Purity assessment and immuno cross-reactivity analyses

Premium Serum & Vaccines Pvt. Ltd., Pune

5,09,152.00

4.

Apr 2018

Mar 2021

Development of functionalized nanoparticles-based novel diagnostic kit for the detection of species-specific snake envenomation

DBT Tata Innovation Fellowship

18,00,000.00

5.

Sep 2018

Mar 2020

Pharmacological studies of recombinant and mutant fibrin(ogen)olytic protease(s) for the prevention and/or treatment of hyperfibrinogenemia associated cardiovascular disorders

DBT, New Delhi

26,04,400.00  

6.

Jun 2018 

Apr 2021

Development of snake venom toxins-targeted specific novel antivenom

BIRAC-PACE

38,00,000.00 

7.

Feb 2018 

Jan 2021

Studies on epidemiology, hospital management of snakebite, and standardization of laboratory tests for assessment of efficacy and quality control of commercial antivenom manufactured in India and in ASEAN countries

DST-SERB (Under ASEAN)

46,43,800.00 

8.

Dec 2014

Dec 2018

Venomics and antivenomics of Indian Cobra and Russell's viper: implications in drug discovery and quality control of antivenoms

DBT, New Delhi under Unit of Excellence in NER-2013 scheme

1,32,20,000.00

9.

Oct 2016

Jun 2018

Development of a cost-effective, novel antithrombotic anticoagulant herbal drug and standardization of its biomarker assisted quality Control

BIRAC-BIG project

49,75,000.00

10.

Apr 2017

Mar 2018

Assessment of purity and contaminating protein(s) in equine polyvalent anti snake venom manufactured by Premium Serum & Vaccines Pvt. Ltd., Pune

Premium Serum & Vaccines Pvt. Ltd., Pune

4,05,750.00

11.

Dec 2014

Mar 2018

Discovering novel drug formulations from non-toxic, potent anticoagulant components of snake venom for the prevention and/or treatment of cardiovascular disease (CVD).

DBT, New Delhi under National Bioscience Award for Career Development-2013

1,50,000.00

12.

Dec 2014

Nov 2017

Application of snake venom toxins labeled with functionalized nanoparticles for detecting endogenous targets in cells and ex vivo tissues with prospects for the development of novel diagnostic and therapy tools

DBT , New Delhi under Indo-Russia collaborative project

45,60,000.00

13.

May 2014

Apr 2016

Proteomics study of aromatic hydrocarbon degradation enzymes of some selected bacterial strain prospecting strategies for environmental bioremediation

ONGC-CPBT, Tezpur University

7,06,000.00

14.

Apr 2011

Sep 2014

Assessment of thrombolytic potential and anticancer activity of fibrinolytic enzymes purified from Russell’s viper venom and bacteria isolated from NE-India

DBT, New Delhi

1,20,86,000.00

15.

Sep 2010

Apr 2011

Demonstration of novelty of protease produced by selected bacteria isolated from North-east India.

DBT, New Delhi

7,14,000.00

16.

Oct 2009

Sep 2014

Strengthening of biotechnology teaching, research, and training in Assam with special reference to Tezpur University

DBT special project , New Delhi

2,98,00,000.00 (to the Department)

17.

Apr 2009

Mar 2014

Microbial enzymes, biosurfactant and probiotics (under SAP, DRS-I).

UGC, New Delhi

42,00,000.00 (to the Department)

18.

Nov 2005

Oct 2008

Exploration of potential microbes from North-east India for the production of three commercially important enzymes- protease, amylase   and cellulose.

DBT, New Delhi

8,94,000.00

19.

Mar 2005

Feb 2008

Isolation, biochemical and pharmacological characterization of pro-coagulant and anti-coagulant proteins from Indian Russell’s viper (Daboia russelli) venom.

UGC, New Delhi

8,67,000.00

20.

Jul 2001

Jun 2004

Isolation, characterization and biological activities of phospholipase A2 enzyme from Indian monocled cobra (Naja kaouthia) venom. 

UGC, New Delhi

6,12,000.00

21.

Oct 1999

Mar 2008

Isolation, characterization and commercial applications of biosurfactant produced by thermophilic and mesophilic bacteria from the soil samples of Assam, India.

ONGC-CPBT

1,88,90,000.00 (to the Department)

22.

Apr 1999

Mar 2000

Identification of some local herbs and plants of Assam for antisnake venom activity.

UGC, New Delhi

15,000.00

Aparup  Patra, Ph.D.
Contact no: 8723024420
Email Id: patra.aparup@iasst.res.in
Doctorate of Philosophy in Snake Venom proteomics and quality assessment of antivenom
Tezpur University, Tezpur
Current Position: Post-Doctoral Fellow, IASST
Research Interest: Snake venom proteomics, quality assessment of antivenom
Dev  Madhubala , M.Sc.
Contact no:  9471351315
Email Id: dmadhu@tezu.ernet.in
Post graduate Degree in Life Science (Biochemistry),
Central University of Punjab, Bathinda.
Current Position: Junior Research Fellow (DST - SERB) , Tezpur University / IASST
Research interest: Characterization of Nerve growth factor from Snake venom
Upasana Puzari, M.Sc.
Contact no:  9954129598
Email Id:  upa2019@tezu.ernet.in
Postgraduate in Biotechnology and Bioinformatics ,
Dibrugarh University, Dibrugarh.
Current Position: Research Scholar , Tezpur University
Research interest : Development of snake venom detection kit
Anushree Roy, M.Sc.
Contact no: 9957082068
Email Id: anushreeroy@iasst.res.in
Post Graduate in Molecular Biology and Biotechnology,
Tezpur University, Tezpur.
Current Position: Research Scholar, IASST
Research interest: Purification and Characterization of microbial biosurfactants
Bhabana Das, M.Sc.
Contact no: 7002836075
Email Id: bhabana@tezu.ernet.in
Post graduate degree in Zoology
Gauhati University, Guwahati
Current Position:  Junior Research Fellow (CSIR) , Tezpur University.
Research Interest: Biochemical and Proteomic analysis of Scorpion venom
Susmita Nath, M.Sc.
Contact no:7002855453
Email Id: nathsusmita@iasst.res.in
Post Graduate degree in Biotechnology,
Gauhati University, Guwahati.
Current Position: Research Scholar, IASST
Paran Baruah, M.Sc.
Contact no: 7708118304
Email Id: pbdbuc30@iasst.res.in
Post Graduate degree in Biotechnology,
Annamalai University, Chidambaram.
Current Position: Research Scholar ,IASST
Research Interest : Biochemical assessment of Mushroom
Hirakjyoti Kakoti , M.Sc.
Contact no: 9678984357
Email Id: hirak19@tezu.ernet.in
Post graduate Degree in Zoology,
Assam University, Silchar.
Current Position: Research Scholar , Tezpur University
Research interest:  Proteomics and antivenomics of Snake venom
Nitisha Boro, M.Sc.
Contact no: 7896774952
Email Id: nitisha@tezu.ernet.in
Post graduate Degree in Biotechnology,
Bodoland University, Kokrajhar.
Current Position: Junior Research Fellow (CSIR), Tezpur University
Research interest: Bacterial recombinant protease and its industrial application
Rahul Kumar, M. Sc
Contact no. : 9678749699
Email ID: kumrrl210@gmail.com
Post graduate degree in Zoology,
Cotton University, Guwahati.
Current position: Research scholar, IASST
Research Interest: Potency of natural and synthetic compounds as antidotes for neurotoxic snake venom
Bhagya Lakhmi Rajbongshi, M.Sc.
Contact No.- 8638252097
Email Id: bhagyalakhmirajbongshi@iasst.res.in
Post Graduate degree in Biotechnology,
Assam Don Bosco University, Tapesia.
Current position: Research Scholar, IASST
Research Interest: Studies on the neuroprotective potential of natural compounds
Rosy Mahato, M.Sc.
Contact no: 7578889506
Email ID: mahatorosy19@gmail.com
Post Graduate degree in Zoology,
Gauhati University, Assam.
Current Position: Research Scholar, IASST
Research Interest: Studies on Neuroprotective potential of synthetic compounds

Two Ph.D. candidates will be selected through the selection test conducted by IASST.