Invited talk by Prof. Anupam Chatterjee

Prof. Anupam Chatterjee, Dept. of Biotechnology & Bioinformatics, North Eastern Hill University (NEHU), Shillong, delivered a lecture at IASST on the topic “The systemic adverse effects of Areca-nut: Evaluation of Carcinogenic Risks and Its Early Detection” on 17th September 2021 through offline and online mode as a part of the National Lecture Series of the program “Aazadi Ka Amrit Mahotsava” celebrated throughout India on the occasion of the 75th year of India’s Independence. The talk was attended by the Hon’ble Director, IASST, Prof. Ashis Kumar Mukherjee including faculty members, research scholars, postdoctoral fellows, and other staff members of the institute. Prof. Anupam Chatterjee is an academician who has been engaged in translating molecular human genetics research and training in the areas of healthcare improvement and innovations. He is a trained geneticist at Banaras Hindu University, Gray laboratory- UK, University of Columbia- USA and Swansea University- UK.

In the North-eastern states of India, incidences of oral and esophageal cancers are eminently high. In Meghalaya, areca nut is consumed raw, in an unprocessed form along with lime paste and a small betel leaf. International Agency for Research on Cancer (IARC) has categorized areca nut as a Group 1 carcinogen. Prof Chatterjee has explained how areca-nut caused cancer and he has revealed through in vivo experiments. His significant contribution unravels the molecular etiology and cellular mechanisms causing oral/esophageal cancer by observing higher chromosome mis-segregation in early carcinogenesis and proposed the importance of precocious anaphase as a screening marker for mitotic check-point defects. Their group has established that over-expression of genes like p53 and Securin play an important role in carcinogenesis. Overall, the program helped to spread scientific awareness among the participants of the program.

Snapshot of talk by Prof. Anupam Chatterjee

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